Hi there,
thanks for reading my post! I think responisve ads is a great tool that should not be neglected by the advertisers.
For one ad group, I usually create 2 text ads and 1 responsive search ad with various headlines (up to 15).
Keep an eye on the ad strenghts as it helps to estimate your ad (I believe this one influences one of the QS components - ad relevance)
I create ad groups ( or sometimes even separate campaign) for each keyword group, where I can customise the headlines and ensure high ad relevance score. I usually do not have issues with it.
If you do - try to rethink the campaign structure and group keywords differently It is very important when it comes to the ad relevance and, as a result, responsive ad strenghts.